https://www.fentonlab.com/news daily 0.75 2025-08-18 https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/f23bc661-94c7-4a1c-b8c5-5e4a55fc3956/WebFig.jpg https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/7cc9d607-f431-4bbf-888c-5c80f26f7645/PXL_20230712_224000727.jpg https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/743c7415-6b21-41bc-abc6-c5e9dbd94096/Redundant-circuit.jpg https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/df3a028c-9b99-470d-a632-55bc3f321acf/Figure+PKM+KIBRA+Structures-WithInhibitors.jpg https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/c36c91e6-16e1-4e41-b510-7d0ea0967efe/PKCil-based-PKMzeta-homologyModel.jpg https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/cb7b7ca2-cd88-493b-8306-695eeaaf4532/iStock-913113356.jpg https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/df434f11-537d-48a0-a43f-b00496b0cff5/SimonCarrillo.jpg https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/8139c101-6d82-49ee-8aff-7c1cdd83b80d/EliottLevy-IMG_5300.jpg https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/6bed8d7b-0507-4f38-adeb-cb17aad3f0f2/SfN2023-Reframing+Neuronal+Coordination-WWTWB.jpg https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/0c1ee7cb-386e-4198-b94d-f290e0c84691/Andre+Fenton-by+RichardChance.jpg https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/a4ff7843-e842-45fc-857f-e98876f34877/image.png https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/94da95eb-6f0f-4b69-88b9-5b4afa3ed76e/Andre+NOVA.jpg https://www.fentonlab.com/news/metabolic-and-physiological-mechanisms-of-pcp-induced-psychosis monthly 0.5 2024-02-08 https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/3057c633-357e-4bbd-9fc4-48947bacb67e/websiteImage.jpg News - Metabolic and physiological mechanisms of PCP-induced psychosis - Make it stand out Schematic of PCP’s proximal metabolic mechanism of action that dysregulates translation. These metabolic effects lead to cognitive control impairments and neuronal spike train discoordination within the hippocampus network without disturbing place fields. The activity vector correlation matrix shows that while CA1 ensemble activity patterns before PCP are self similar, they become uncorrelated under PCP for about 30 min, after which activity toggles between the PCP pattern and the pre-PCP pattern until about 40 min when it settles back to the pre-PCP state. Notice that the PCP ensemble discharge pattern was observed a few times before PCP was ever administered (red arrow heads). Is this what a hallucination would look like? In any case this demonstrates that the PCP did not induce the PCP-activity pattern, PCP only made the paper more likely. https://www.fentonlab.com/news/photacs-works-to-selectively-degrade-proteins-under-light-control-in-hippocampus-slices monthly 0.5 2024-02-08 https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/2f5cab49-27bc-4ea1-982a-b9f4a758856a/WebsiteImage.jpg News - PHOTACs selectively degrade proteins under light control in hippocampus slices - Make it stand out The PHOTAC logic (left) and effect (right). A ligand to a protein of interest (POI) is attached to an E3 ligase ligand via a photo-sensitive linker. Wavelength-specific light switched the PHOTAC between the active and inactive state. In the active state the E3 ligase ligand is available to bind to endogenous E3 ligase and the POI (we targeted CaMKIIalpha) catalyzing ubquitylation of the POI and thus its proteosomal degradation. The CaMKII-PHOTAC effectively attenuated baseline perforate path synaptic function in hippocampal slices only when if the PHOTAC was illuminated. https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/c1db144c-5255-4d60-b48d-cf7b5c12caf6/ClaudiaJou.JPG News - PHOTACs selectively degrade proteins under light control in hippocampus slices - Make it stand out Claudia Jou https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/a27db972-4a2c-49cf-9ec2-e42649ad4f35/AlexGrauPerales.jpg News - PHOTACs selectively degrade proteins under light control in hippocampus slices - Make it stand out Dr. Alejandro Grau-Perales https://www.fentonlab.com/news/can-game-theory-explain-neurobiological-interactions-across-biological-scales monthly 0.5 2024-02-08 https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/1a2efcf2-132a-4d39-8cb7-665221664a1c/Figure3-games-network.jpg News - Can game theory help us understand neurobiological interactions across biological scales? - Make it stand out Schematic neural network as a signaling game.See figure 3 from Fenton et al. 2023. https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/baede585-1ecd-48b8-8995-a5f902eee7b3/JoseHurtado-IMG_3159.jpg News - Can game theory help us understand neurobiological interactions across biological scales? - Make it stand out José Hurtado https://www.fentonlab.com/news/beyond-memory-learning-to-learn monthly 0.5 2024-10-12 https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/219fb7c1-47ca-4ce8-9012-3ca18bcb8dbb/Blog+Post+17.jpeg News - Beyond memory, learning to learn - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.fentonlab.com/news/dentate-spikes-control-dinos-latest monthly 0.5 2024-10-12 https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/a40e4bcb-749f-4caf-a1d0-7b478066a07a/Blog+Post+16+-+Alt+Image.jpg News - Dentate Spikes Control: Dino’s Latest - This image superimposes hippocampal local field potentials on railway tracks controlled by a switch that is overlaid by a dentate spike colored yellow. Railway tracks provide different pathways to distinct destinations, like different hippocampal information processing modes can enable distinctive memory encoding and recollection information processing functions. Externally-controlled railway switches control each train’s destination, whereas prominent medial-entorhinal cortex-originating dentate spikes transiently switch hippocampus information processing from encoding to recollection, like a railway switch diverts a train, this dentate spike event diverts thoughts from the present to the past. https://www.fentonlab.com/news/video-on-cell-press-youtube-channel monthly 0.5 2022-01-18 https://www.fentonlab.com/news/reviewing-the-evidence monthly 0.5 2022-01-18 https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/3420dc7a-80ee-404e-93cb-52d2064adab3/Blog+Post+15.jpg News - Reviewing the evidence - Make it stand out Image credit: Panos Tsokas - LTP-inducing Schaffer Collateral stimulation increases PKMzeta expression (red) and synaptic responses in CA1 https://www.fentonlab.com/news/head-direction-cell-paper-with-jim-ranck monthly 0.5 2024-10-12 https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/f54924f0-2d3f-4d39-ba71-e45c17e1370b/Blog+Post+13.jpg News - Head-direction cell paper with Jim Ranck - Neuron Cover - Exciting to see the Cover image of today's issue of Neuron featuring EunHye's artwork - adaptation of a photo inspired by etak navigation of the Pacific Islanders! https://www.fentonlab.com/news/eunhyes-head-direction-cell-paper-out-in-neuron monthly 0.5 2022-01-18 https://www.fentonlab.com/news/opinion-piece-in-spectrum monthly 0.5 2022-01-18 https://www.fentonlab.com/news/from-a-preview-commentary-to-lebron-james monthly 0.5 2025-08-18 https://www.fentonlab.com/news/check-out-andre-on-nova-wonders monthly 0.5 2022-01-18 https://www.fentonlab.com/news/a-successful-defense-for-dr-milenna-van-dijk monthly 0.5 2022-01-18 https://www.fentonlab.com/news/congrats-to-dino-on-his-new-eeg-paper monthly 0.5 2022-01-18 https://www.fentonlab.com/news/place-cell-papers-on-fragile-x-mice-are-online monthly 0.5 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https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/f8802718-7d59-426c-ab59-0da14af92ded/2023-08-23-63.jpg https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/97d03613-8007-4d47-816c-9fc6595c2e04/20180318-ny-wall-small.jpg https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/c8f1fa01-8c61-4137-9791-a3623fc7dea8/Jaini_Pic.jpg https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/3b514186-09cd-4c0a-bd33-3a2af3da0498/AndreFenton-photo.jpg Our Team - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/de5b62f8-91fe-4ee9-b8a3-923ec95d5ebb/BudPic.jpg Our Team - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.fentonlab.com/the-space daily 0.75 2022-01-12 https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/2529f032-7e4e-4a4d-9433-c74c5388f938/Sade%CC%81-+Fenton-5+copy.jpg The Space https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/24a3f4d2-2812-4093-b7bf-16a04197b4bd/remapping.png The Space https://www.fentonlab.com/home daily 1.0 2024-10-13 https://www.fentonlab.com/about daily 0.75 2022-01-11 https://images.squarespace-cdn.com/content/v1/61a6d088a246256a48f10510/5a541dec-eddd-4b81-b720-48d71e0365bf/edited+%281+of+1%29-2.jpg About - ‘What we think we become’. We study how brains store experiences as memories, and how the expression of knowledge activates information that is relevant without activating what is irrelevant. Our laboratory uses molecular, electrophysiological, behavioral, engineering, and theoretical methods to investigate these fundamental and interrelated issues in neuroscience. https://www.fentonlab.com/contact-us daily 0.75 2022-01-11 https://www.fentonlab.com/mission-and-values daily 0.75 2022-01-17 https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1618497259178-6XJGK9GR6YAVBQL5L519/20140301_Trade-151_012-2.jpg Mission and Values https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1607694583486-2PQT0LQ193RL7MCB6DX4/20140228_Trade+151_0046.jpg Mission and Values https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1607694644871-IC85FNH781UNZSZEGHDR/Aro+Ha_0428.jpg Mission and Values https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1607638148090-Y6OFDI575CM3NQV732RJ/Large+JPG-Aro+Ha_0387.jpg Mission and Values https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1607628784608-5D22G9GPLHDSAB2IXC2G/Large+JPG-Aro+Ha_0638.jpg Mission and Values https://www.fentonlab.com/video-place-avoidance-and-yoked-shock-comparison daily 0.75 2022-01-17 https://www.fentonlab.com/video-place-avoidance daily 0.75 2022-01-16